Featured Research Project
| June 2008: Elastin Fibers | ||||||||||||||
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Robert
P. Mecham, Ph.D., Alumni Endowed
Professor of Cell Biology and Physiology, professor
of pediatrics and of medicine, was elected to
the Section on Biological Sciences in October
2007 for distinguished contributions to the field
of elastin fibers, particularly for analysis of
elastin fiber composition and assembly, and the
cell biology of elastin.
Image at left: Mouse lung stained with antibodies to elastin (green) and and the endothelial cell marker flk (red). Dapi was used to mark nuclei (blue). Antibody images were superimposed over DIC image of same tissue section. Flk-positive endothelial cells were detected throughout the lung mesenchyme as interconnected strands associated with vasculogenic vessels that are forming during this period. Staining with the elastin antibody showed strong signal in airway smooth muscle and in well-developed blood vessels. (Image provided by Dr. Sean McLean) |
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